The BioTense Perfusion Bioreactor is a next generation instrument to help tissue engineers and cell biologists perform high resolution investigation in mechanobiology. Unique to the BioTense is its ability to apply uniaxial mechanical stimulation and directly observe cell/matrix interaction at high magnification over long periods of time. BioTense is a self-contained instrument capable of applying uniaxial forces to 7N and elongations of 25mm. The Bioreactor sits a top the XYZ stage of an inverted microscope.